keyword :
分类
Products
  • Name: Oenothera Biennis Oil Soft Capsules
  • Add time: 2015-05-15
  • Views : 130

[Drug Name]
Generic Name:月见草油胶丸
English name:Oenothera Biennis Oil Soft Capsules
Pinyin:Yuejiancaoyou Jiaowan
Ingredient
Chemical name: cis-6,9,12-octadecatrienoic acid.
Chemical Structure:
[Character]
This product capsules, the contents of yellow to orange-yellow, oily liquid.
Indications
For the prevention and treatment of atherosclerosis, lower blood lipids.
[Specification]
0.3g (evening primrose oil dollars)
Dosage
Oral.
A 5 to 6, 2 times a day, or as directed.
[Adverse reactions]
Individual patients see initial oral medication nausea, they dilute and other adverse reactions to medication can be improved.
Taboo
1. Disable this allergy.
2. Patients with hemorrhagic disease is disabled.
3. pregnancy.
Precautions
Characters change, color brown Not applicable.
[Pregnant women and lactating women drug]
Pregnant women, disabled.
Pediatric Use
It is not clear.
[Geriatric medicine]
It is not clear.
Drug interactions
It is not clear.
Overdosage
It is not clear.
Pharmacology and Toxicology
1. Pharmacology
The product is rich in γ- linolenic acid (GLA), can be converted into PEG2, PGI2, PGF2a, with a significant lipid-lowering and anti-platelet aggregation. γ- linolenic acid has a significant cholesterol-lowering effect, which is 163 times the potency of linoleic acid. Evening primrose oil can make fat rat serum total cholesterol, LDL cholesterol, very low density lipoprotein cholesterol, while HDL cholesterol levels were significantly increased. High-density lipoprotein cholesterol changes are due to increased high-density lipoprotein subfraction cholesterol levels, particularly high-density lipoprotein cholesterol levels subgroup no significant change. To Wistar rats fed high cholesterol modeling agent or acetic acid causes high cholesterol pathological model, the results show that evening primrose oil and its sodium salt has strong lipid-lowering and anti-atherosclerosis effect. This product can be involved in the synthesis of prostaglandins and balance. It can still inhibit platelet aggregation and platelet synthesis of thromboxane A2 (TXA2), thus changing the ratio of TXA2 / PGI2, with the role of prevention and treatment of thrombotic cardiovascular diseases. γ- linolenic acid on brown adipose tissue has a stimulating effect and promote the activity of mitochondria of brown fatty acids, consume too many calories to lose weight and achieve a certain effect.
2. Toxicology
Evening primrose oil failed to determine the acute toxicity test in mice LD50, for rabbits by daily 3g / kg, 2 times daily dose continuous administration of 120 days were killed, did not find the heart, liver, kidney, spleen, adrenal gland, thymus any pathological changes.
Pharmacokinetics
γ- linolenic acid (GLA) is one of the essential fatty acids in the body can be metabolized into two high -γ--linolenic acid (DGLA) or arachidonic acid (AA), and then converted to prostaglandins (PGs) and white three ene (LT). γ- linolenic acid (GLA) and its series of metabolites in the immune system, cardiovascular system, reproductive system, endocrine system, we have a wide range of physiological effects.
[Storage]
Shading, sealed and stored in a dry place.
[Packaging]
Blister packaging, 10 / plate; carton packaging, 4 plates / box.
Blister packaging, 10 / plate; carton packaging, 5 boards / box.
[Validity]
Provisional 18 months
[Executive standard]
State Food and Drug Administration National Drug Standards WS-10001- (HD-0599) -2002
Approval Number
Zhunzi H21022641
Manufacturer
Company Name: Shenyang Hongqi Pharmaceutical Co., Ltd.
Production Address: Shenyang Hunnan New District envelope 6th Street
Postal Code: 110179
Phone Number: (024) 2,378,626,023,786,261
Fax: (024) 23786263

 

The above is for reference
If you have questions can contact the manufacturer